Colorado vs. Georgia Tech prediction, odds: 2025 Week 1 college football picks by expert on 62-42 roll

The Colorado Buffaloes will open their third season under head coach Deion Sanders when they host the Georgia Tech Yellow Jackets on Friday. The Buffs went 9-4 in 2024, but lost Heisman Trophy winner Travis Hunter and quarterback Shedeur Sanders to the NFL. Former Liberty quarterback Kaidon Salter was named the starter this week. The Yellow Jackets are looking to build off a 7-6 record in 2024 as they enter their fourth season under head coach Brent Key. Georgia Tech returns nine starters including quarterback Haynes King and running back Jamal Haynes. 

Kickoff is set for 8 p.m. ET at Folsom Field in Boulder, Colo. The Yellow Jackets are 3.5-point favorites in the latest Georgia Tech vs. Colorado odds, while the over/under for total points scored is 51.5, down three points from the opener. Before making any Colorado vs. Georgia Tech picks, be sure to see what SportsLine expert Mike Tierney has to say. New users can also target the latest DraftKings promo code, which offers $300 in bonus bets instantly plus over $200 off NFL Sunday Ticket:

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Tierney had a tremendous 2024 college football season in which he finished 62-42 (plus $1,539 for $100 players). Anyone following could’ve seen huge returns.

Now, Tierney has set his sights on Georgia Tech vs. Colorado and just locked in his picks and college football predictions. You can head to SportsLine now to see his picks. Here are several college football odds and college football betting lines for Georgia Tech vs. Colorado:

Why Colorado can cover

The Buffs were outstanding at home in 2024. Colorado posted a 5-1 record at Folsom Field, with its only loss coming by three points against Kansas State. The altitude in Boulder (5,360 feet) could play a role late in the game with Georgia Tech doing the bulk of its training much closer to sea level.

The Buffs are breaking in a new quarterback in 2025, but experience shouldn’t be an issue. CU is turning to transfer Kaidon Salter, who spent the last four years at Liberty. In his three seasons as the Flames’ starter, Salter threw for 5,887 yards, 56 touchdowns, and 17 interceptions, and rushed for 2,013 yards and 21 touchdowns. His best season came in 2023, when he threw for 2,876 yards, 32 touchdowns and six interceptions, and rushed for 1,089 yards and 12 scores. See which team to back at SportsLine. 

Why Georgia Tech can cover

Georgia Tech enters the 2025 season under the steady leadership of coach Brent Key, who will be in his third full year leading the progrom. The Yellow Jackets battled inconsistency in 2024, but proved they could play with the best teams in the country when things were clicking. In Georgia Tech’s regular season finale, it pushed in-state rival Georgia to the brink before losing 44-42 in an eight overtime classic.

Georgia Tech will be buoyed by the return of gritty quarterback Haynes King and one of the nation’s top offensive lines featuring standout Keylan Rutledge. When healthy, King has proven to be one of the top dual-threat quarterbacks in college football. The Yellow Jackets also return leading rusher Jamal Haynes, who ran for 944 yards and nine scores in 2024. See which team to back at SportsLine, and new users can also check out the latest bet365 bonus code to get $200 in bonus bets after placing a $5 bet:

How to make Georgia Tech vs. Colorado picks

Tierney has analyzed Colorado vs. Georgia Tech from every angle and he’s leaning Under on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing what it is, and which side to back, at SportsLine.

So, who wins Colorado vs. Georgia Tech on Friday, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the Colorado vs. Georgia Tech spread to jump on, all from the expert who 62-42 in his college football picks in 2024, and find out.